When I click on the file and opt to Save As using IE7 and Vista I direct the
file to go into my Download folder but then it immediately disappears,
whether I click Run or Save, the file appears to be downloading just fine and
then it disappears entirely.
I have been using FireFox without issue as the solution, but I would like to
be able to use IE7 as I've always done.  

I'll give you a summary of the things I've tried to fix the problem:
* Deleting Temporary Internet Files in IE
* Deleting Windows Temp folders
* Shutting down all non-microsoft spyware/antivirus programs
* Checking for viruses/spyware with AVG, Windows
Defender, SpyBot S&D 1.5.2
* Installing all latest chipset drivers available
* Installing all Windows Updates including Vista SP1
* Running IE7 in "no addons" mode
* Resetting IE7
I had a suspicion that this may have occurred after a recent Windows update
and I've also tried Restoring to a date before the one I suspected, but this
didn't resolve the problem.

Any advice would be greatly appreciated.
TIA
Toppers