Most email providers have a way to do that on their server. Log on via
their email webpage to turn it on/off.
That way, you don't have to leave your computer running while you are away.

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http://get.live.com/wlmail/overview
> Hi all, I am going away on holday in just over a weeks time and was
> wondering
> if there was a way of setting up a automated reply mail to let my clients
> know I am away, that I have recieved their mails and will reply on my
> return?
> Any help would be much appreciated
Ronnie - 12 May 2008 22:55 GMT
Thank you!. I will check that out tomorrow!
> Most email providers have a way to do that on their server. Log on via
> their email webpage to turn it on/off.
[quoted text clipped - 6 lines]
> > return?
> > Any help would be much appreciated