That file belongs to the My Websearch toolbar, which is malware. If you have
recently cleaned up your computer to remove malware, then a reference was
left in Startup. See below for how to manage your Startup. If you have
*not* recently cleaned up your computer, you need to do so. See below for
general malware removal steps.

http://www.elephantboycomputers.com/page2.html#Removing_Malware

Starup management - Start Orb>Start Search box>msconfig [enter]

If you are prompted for an administrator password or for a confirmation,
type the password, or click Continue. Then see what is on the Startup tab.
You don't need to restart immediately, but the next time you do you'll get
a dialog saying you've used the Utility. Usually in Vista this will be
blocked by Windows Defender and you'll need to allow it so you can then
tick the box that says in effect, "don't bother me about this again".

Important - Do not use the System Configuration Utility to stop processes.
Instead, use Start>Run>services.msc [enter] and do not stop any services
unless you really, really know what you're doing.

The free Autoruns program is very useful for managing your Startup -
http://www.microsoft.com/technet/sysinternals/default.mspx - Autoruns

Standard disclaimer: I can't see and test your computer myself, so these are
just suggestions based on many years of being a professional computer tech;
suggestions based on what you've written. You should not take my
suggestions as a definitive diagnosis. If you can't do the work yourself
(and there is no shame in admitting this isn't your cup of tea), take the
machine to a professional computer repair shop (not your local equivalent
of BigComputerStore/GeekSquad). If possible, have all your data backed up
before you take the machine into a shop.

Malke